Which is the best muscle relaxant for RSI in the field? š
Letās dive into a recent study comparing Succinylcholine and Rocuronium for RSI in prehospital care, including their mechanisms of action and implications for EMS professionals.
šØ Study Key Points:
āAnalyzed 5179 EMS cases from Seattle Fire over a 7-year period (2015 to 2022).
ā Succinylcholine group: 329 patients
ā Rocuronium group: 1,146 patients
ā Excluded: Cardiac arrest cases, no prior blockade, under 18, both drugs used, video laryngoscopy, missing capnography
Results Summary:
ā Laryngoscopy views: No difference.
ā Time to:
a. First attempt: Sux (57s) vs. Roc (83s).
b. Successful intubation: Sux (132s) vs. Roc (162s).
ā Bougie use: Sux (62%) vs. Roc (94%).
ā First pass success: Similar (Sux 84%, Roc 83%).
ā Hypoxemia: Comparable (Sux 25%, Roc 23%).
š Conclusion of this paper:
ā” Prehospital use of either rocuronium or succinylcholine is associated with similar:
1. Similar Cormack-Lehane grades
2. First-pass success rates
3. Rates of peri-intubation hypoxemia
Analysis :
āWell-executed study on a crucial topic.
ā Excluded video laryngoscopy (VL) cases.
ā The 23-25% hypoxemia rates highlight Dr. Jarvis's 2018 publication on (delayed sequence, intubation) DSI.
- He demonstrated a reduction in hypoxia from 44% down to 3.5% using DSI.
- Link: https://pubmed.ncbi.nlm.nih.gov/29530653/.
ā It is recommended that more agencies to adopt DSI, showing significant benefits over RSI.
ā¼ Whatās your experience? Do you prefer one over the other? š£ļøš©āššØāš